
Hand holding three vape juice bottles
| Principle | Description |
| Ingredient Disclosure Requirements | Regulatory agencies require clear disclosure of all ingredients, especially concerning toxic aroma chemicals. |
| Minimalist Approach to Formulations | Simplifying ingredient lists helps in compliance with regulations and reduces testing costs. |
| Shorter, Transparent Formulations | In EU markets, strict rules have led to the adoption of shorter and clearer ingredient lists. |
| Study Focus | Findings |
| Cytotoxicity of E-cigarettes | E-cigarettes are cytotoxic to various cells, with certain flavors showing increased toxicity. |
| Ingredient Complexity | E-liquids often contain multiple flavorants, complicating health impact assessments. |
| Health Impact Assessment | Lack of ingredient transparency can lead to exposure to harmful substances. |
| Flavouring ingredient | Prevalence (% of total e-liquids) | Median concentration (mg/10 mL) | Flavour description |
| Vanillin | 35.2 | 7.0 | Sweet, powerful, creamy, vanilla-like |
| Ethyl maltol | 32.0 | 5.9 | Sweet, fruity-caramellic, cotton candy |
| Ethyl butyrate | 28.4 | 3.6 | Ethereal, fruity with buttery-pineapple-banana notes |
| Ethyl acetate | 23.2 | 1.1 | Ethereal, sharp, wine-brandy-like |
| Maltol | 22.8 | 1.3 | Sweet, fruity, berry, strawberry, caramellic |
| Ethyl vanillin | 19.4 | 6.8 | Intense, sweet, creamy, vanilla-like |
| Furaneol | 19.3 | 2.0 | Fruity, caramelised, roasted, pineapple-strawberry |
| Methyl cyclopentenolone | 18.3 | 2.0 | Very strong, caramellic-maple, lovage |
| γ-Decalactone | 18.2 | 0.5 | Coconut-peach |
| Cis-3-hexenol | 17.8 | 1.5 | Strong, fresh, green, grassy |
| Isoamyl acetate | 16.3 | 2.3 | Sweet, fruity, banana, pear |
| Ethyl 2-methyl butyrate | 16.0 | 2.2 | Strong, green, fruity, apple with strawberry notes |

Bar chart of vape flavor ingredient prevalence

Vape pen with cannabis buds

Live CBD vape cart packaging
| Ingredient Name | Purpose |
| Propylene Glycol | Carrier/Base |
| Vegetable Glycerin | Carrier/Base |
| Vanillin | Flavoring |
| Ethyl Maltol | Sweetener/Flavoring |
| Sucralose | Sweetener |
| Food-grade Colorant | Visual Appeal |
| Compliance Step | Purpose |
| Submit ingredient list to FDA | Regulatory review and public health check |
| Disclose ingredient quantities | Ensure accurate labeling |
| Use clear, specific language | Build consumer trust |
| Update labels as regulations change | Maintain ongoing compliance |
| What’s Working? | What’s Not Working? |
| Simple, consumer-friendly labeling using common terms like 'Natural and Artificial Flavors' aligns with industry standards and is recognized by consumers. | Listing chemical names of all flavoring ingredients can confuse or intimidate consumers, as seen in regulations from Oregon, New York, and Missouri. |
| What’s Working? | What’s Not Working? |
| Following the FDA’s Food Safety Modernization Act (FSMA) for quality plans ensures hazards are identified and controlled. | Overly broad testing requirements for non-cannabis-derived flavors are redundant and economically unviable. |

Bar chart on vape consumer trust
| Brand | Commitment to Transparency |
| Juul Labs | Strict quality control and high-grade ingredients. |
| Innokin | Adherence to health and safety standards in production. |
| Lost Mary MO20000 | High ingredient transparency and strong safety features. |
The business scope includes licensed projects: food additive production. General projects: sales of food additives; manufacturing of daily chemical products; sales of daily chemical products; technical services, technology development, technical consultation, technology exchange, technology transfer, and technology promotion; biological feed research and development; industrial enzyme preparation research and development; cosmetics wholesale; domestic trading agency; sales of sanitary products and disposable medical supplies; retail of kitchenware, sanitary ware and daily sundries; sales of daily necessities; food sales (only sales of pre-packaged food).
Copyright ©Guangdong Unique Flavor Co., Ltd.All Rights Reserved. Privacy Policy Return and Exchange Policy